Profile – Sulston Zone – Wellcome Trust Sanger Institute

Education:

Saraswati Sishu Mandir (Lucknow, India)
Qualifications:

University of Lucknow (Lucknow, India): B.Sc. Biology (1994-97), M.Sc. Biochemistry (1997-99). Indian Institute of Science (Bangalore, India) : Ph.D. in Molecular Endocrinology (1999-2005)
Work History:

After Ph.D. in understanding how ovaries function in mammals I worked at Baylor College of Medicine, USA (2005-2006) and then Columbia University, New York, USA (2006-2010) as a scientist
Current Job:

Bone Biology

Read more

I work on bones. The bones in our body are like houses. A house is constantly deteriorating due to external factors, such as sunlight and rain, internal factors such as rusting or woodworm. In the same way our bones can deteriorate due to factors that originate within and outside the bone. For example, alterations in the levels and/or action of molecules (hormones) can lead to changes in bone mass. The best example of this phenomenon is the loss of oestrogen – an ovary-derived hormone – after menopause, which can lead to osteoporosis. I aim to identify some of these factors that regulate bone through the use of genomic and proteomic approaches. This may help to further the understanding of the biology of bone and ultimately identify new targets for to cure bone diseases.
My Typical Day:

Bus to work, email, do experiments, talk to group members, do more experiments, grab a quick lunch in between, drink a coke, write, think and brainstorm the ideas.
What I'd do with the prize money:

Genome sequencing (RNA and DNA) has identified how many genes and proteins are there and when they are expressed, my group uses this information to link genes expressed in distant organs.

Vijay Yadav